Dear Dr. Roach: I’ve been on Cymbalta for 16 years. I had had panic attacks, and my doctor suggested it, along with talk therapy. After a year, my therapist told me they weren’t made to be used long term and I should eventually wean myself off them. I did at one point and was good for about seven months, at which point the panic attacks came back with a vengeance. I started taking them again and am now afraid to stop. They make me feel less than worthy, in the sense that I can’t do well in life without them. I take 10 milligrams every day or five days a week as I forget occasionally. Are there long-term effects taking this drug?