Will Sharp (Yahya Abdul-Mateen II), the lead character of Ambulance, needs money. Fast. He’s a veteran who can’t get the healthcare he needs just as his wife (and the mother of his child) desperately requires an experimental surgery. This is when Will turns to his brother, Danny Sharp (Jake Gyllenhaal), a criminal that Will has become distant with. Will never wanted to get back into the game of robberies and crime, but with his bank account running so low, he has no choice. He joins up with Danny to rob a bank in Los Angeles, which should be an easy job. Unfortunately, things go south quickly and the duo end up hijacking an ambulance with EMT Cam Thompson (Eiza Gonzales) and a mortally wounded cop onboard. Now this unlikely quartet is trapped in an ambulance speeding down every road in Los Angeles pursued by an army of cops. There’s no easy way out here, if there is even a possibility of exiting.